Low-density lipoprotein aggregation predicts adverse cardiovascular events in peripheral artery disease

SP Heffron, MK Ruuth, Y Xia, G Hernandez, L Äikäs… - Atherosclerosis, 2021 - Elsevier
Background and aims Peripheral artery disease (PAD) is a systemic manifestation of
atherosclerosis that is associated with a high risk of major adverse cardiovascular events
(MACE). LDL aggregation contributes to atherosclerotic plaque progression and may
contribute to plaque instability. We aimed to determine if LDL aggregation is associated with
MACE in patients with PAD undergoing lower extremity revascularization (LER). Methods
Two hundred thirty-nine patients with PAD undergoing LER had blood collected at baseline …