Post-translational modifications (PTMs) produce significant changes in the structural
properties of intrinsically disordered proteins (IDPs) by affecting their energy landscapes.
PTMs can induce a range of effects, from local stabilization or destabilization of transient
secondary structure to global disorder-to-order transitions, potentially driving complete state
changes between intrinsically disordered and folded states or dispersed monomeric and
phase-separated states. Here, we discuss diverse biological processes that are dependent …