Atherosclerosis is a chronic inflammatory disease of the arterial wall characterized by lipid
deposition, plaque formation, and immune cell infiltration. Innate and adaptive immune cells
infiltrate the artery during development of the disease. Moreover, advanced disease leads to
formation of artery tertiary lymphoid organs in the adventitia (Grabner et al., 2009; Hu et al.,
2015). Various and diverse types of immune cells have been identified in the aorta
adventitia vs atherosclerotic plaques (Elewa et al., 2016; Galkina et al., 2006; Lotzer et al …