[HTML][HTML] Instrumentation to study myofibril mechanics from static to artificial simulations of cardiac cycle

PG Vikhorev, MA Ferenczi, SB Marston - MethodsX, 2016 - Elsevier
Many causes of heart muscle diseases and skeletal muscle diseases are inherited and
caused by mutations in genes of sarcomere proteins which play either a structural or
contractile role in the muscle cell. Tissue samples from human hearts with mutations can be
obtained but often samples are only a few milligrams and it is necessary to freeze them for
storage and transportation. Myofibrils are the fundamental contractile components of the
muscle cell and retain all structural elements and contractile proteins performing in …

[PDF][PDF] 2 Instrumentation to [24_TD $ DIFF] study myofibril 3 mechanics from static to artificial simulations 4 of cardiac cycle

PG Vikhorev, MA Ferenczi, SB Marston - 2016 - researchgate.net
Many causes of heart muscle diseases and skeletal muscle diseases are inherited and
caused by mutations in genes of sarcomere proteins which play either a structural or
contractile role in the muscle cell. Tissue samples from human hearts with mutations can be
obtained but often samples are only a few milligrams and it is necessary to freeze them for
storage and transportation. Myofibrils are the fundamental contractile components of the
muscle cell and retain all structural elements and contractile proteins performing in …