[HTML][HTML] The underlying mechanisms for development of hypertension in the metabolic syndrome

H Yanai, Y Tomono, K Ito, N Furutani, H Yoshida… - Nutrition journal, 2008 - Springer
H Yanai, Y Tomono, K Ito, N Furutani, H Yoshida, N Tada
Nutrition journal, 2008Springer
High blood pressure is an important constituent of the metabolic syndrome. However, the
underlying mechanisms for development of hypertension in the metabolic syndrome are
very complicated and remain still obscure. Visceral/central obesity, insulin resistance,
sympathetic overactivity, oxidative stress, endothelial dysfunction, activated renin-
angiotensin system, increased inflammatory mediators, and obstructive sleep apnea have
been suggested to be possible factors to develop hypertension in the metabolic syndrome …
Abstract
High blood pressure is an important constituent of the metabolic syndrome. However, the underlying mechanisms for development of hypertension in the metabolic syndrome are very complicated and remain still obscure. Visceral/central obesity, insulin resistance, sympathetic overactivity, oxidative stress, endothelial dysfunction, activated renin-angiotensin system, increased inflammatory mediators, and obstructive sleep apnea have been suggested to be possible factors to develop hypertension in the metabolic syndrome. Here, we will discuss how these factors influence on development of hypertension in the metabolic syndrome.
Springer