Strength-training effectively alleviates skeletal muscle impairments in myotonic dystrophy type 1

MP Roussel, LJ Hébert, E Duchesne - Neuromuscular Disorders, 2020 - Elsevier
Abstract Myotonic dystrophy type 1 (DM1) is a multisystemic disease characterized by
progressive muscle weakness. The aim of this project is to evaluate the effects of a 12-week
lower limb strength training program in 11 men with DM1. Maximal isometric muscle
strength, 30-second sit-to-stand, comfortable and maximal 10-m walk test (10 mwt) were
evaluated at baseline, 6 and 12 weeks, and at 6 and 9 months. The one-repetition maximum
strength evaluation method of the training exercises was completed at baseline, 6 and 12 …