The glomerular basement membrane (GBM) is a specialized extracellular matrix (ECM)
compartment within the glomerulus that contains tissue-restricted isoforms of collagen IV
and laminin. It is integral to the capillary wall and therefore, functionally linked to glomerular
filtration. Although the composition of the GBM has been investigated with global and
candidate-based approaches, the relative contributions of glomerular cell types to the
production of ECM are not well understood. To characterize specific cellular contributions to …