Do CD4+ Foxp3+ Treg cells correlate with transplant outcomes: a systematic review on recipients of solid organ transplantation

J Shan, Y Guo, L Luo, J Lu, C Li, C Zhang, Y Huang… - Cellular …, 2011 - Elsevier
Regulatory T cells (Tregs) are considered to be critical for the induction of transplant
tolerance. Tregs counts were measured in blood, biopsy and urine sample after
transplantation in many studies. Although not unanimous, some studies have suggested that
Tregs is associated with better outcome and can also serve as an immune marker to predict
the individual risk of rejection and identify tolerant patients. In this study, we systematically
reviewed the correlation between Tregs and transplant outcomes, identifying if Tregs can …