[PDF][PDF] The PTPN22 C1858T variant as a risk factor for rheumatoid arthritis and systemic lupus erythematosus but not for systemic sclerosis in the Colombian …
M Ramirez, G Quintana, LM Diaz-Gallo… - Clinical and …, 2012 - clinexprheumatol.org
Clinical and Experimental Rheumatology-Incl Supplements, 2012•clinexprheumatol.org
Objectives C1858T single nucleotide polymorphism in PTPN22 encoding the R620W allele
variant of Lyp-PTPN22 (a protein phosphatase negatively regulating T-cell activation) has
been associated with autoimmunity. This work has investigated the possible association
between PTPN22 C1858T (rs2476601) polymorphism and rheumatoid arthritis (RA),
systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in a Colombian
population.
variant of Lyp-PTPN22 (a protein phosphatase negatively regulating T-cell activation) has
been associated with autoimmunity. This work has investigated the possible association
between PTPN22 C1858T (rs2476601) polymorphism and rheumatoid arthritis (RA),
systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in a Colombian
population.
Objectives
C1858T single nucleotide polymorphism in PTPN22 encoding the R620W allele variant of Lyp-PTPN22 (a protein phosphatase negatively regulating T-cell activation) has been associated with autoimmunity. This work has investigated the possible association between PTPN22 C1858T (rs2476601) polymorphism and rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in a Colombian population.
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