Animal models using lymphocytic choriomeningitis virus
M von Herrath, JL Whitton - Current Protocols in Immunology, 2000 - Wiley Online Library
M von Herrath, JL Whitton
Current Protocols in Immunology, 2000•Wiley Online LibraryThis unit includes protocols for inducing systemic infection and persistent infection of mice
with lymphocytic choriomeningitis virus (LCMV). Methods used to measure T cell responses
to LCMV are then described. A protocol to assess anti‐LCMV immunity in vivo is also
included. Support protocols for preparing LCMV stocks and measuring LCMV titers using a
plaque assay are also included. Finally, a support protocol for detecting anti‐LCMV
antibodies by ELISA is presented.
with lymphocytic choriomeningitis virus (LCMV). Methods used to measure T cell responses
to LCMV are then described. A protocol to assess anti‐LCMV immunity in vivo is also
included. Support protocols for preparing LCMV stocks and measuring LCMV titers using a
plaque assay are also included. Finally, a support protocol for detecting anti‐LCMV
antibodies by ELISA is presented.
Abstract
This unit includes protocols for inducing systemic infection and persistent infection of mice with lymphocytic choriomeningitis virus (LCMV). Methods used to measure T cell responses to LCMV are then described. A protocol to assess anti‐LCMV immunity in vivo is also included. Support protocols for preparing LCMV stocks and measuring LCMV titers using a plaque assay are also included. Finally, a support protocol for detecting anti‐LCMV antibodies by ELISA is presented.
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