Eating disorders and the serotonin connection: state, trait and developmental effects

H Steiger - Journal of Psychiatry and Neuroscience, 2004 - jpn.ca
Alterations in brain serotonin (5-hydroxytryptamine [5-HT]) function are thought to contribute
to diverse aspects of eating disorders, including binge eating, perfectionism, impulsivity and
mood-regulation problems. In addition, 5-HT anomalies in individuals with eating disorders
are believed to have multiple determinants associated with secondary (state-related) effects
of their nutritional status, hereditary effects (related to such trait variations as impulsivity or
perfectionism) and, possibly, long-term neurobiologic sequelae of developmental stressors …