Influence of atmospheric versus reduced oxygen concentration on development of human blastocysts in vitro: a prospective study on sibling oocytes
B Kovačič, V Vlaisavljević - Reproductive biomedicine online, 2008 - Elsevier
Numerous studies show the beneficial effect of reduced oxygen on the culture of animal
embryos in vitro. However, few similar studies have been carried out in humans, and the
conclusions from these were contradictory. Using sibling human oocytes, a prospective
study was carried out to analyse the effect of 5 and 20% oxygen on prolonged development
of embryos. The outcomes measured were fertilization rate and proportion of
morphologically optimal embryos, blastocysts and optimal blastocysts developing on day 5 …
embryos in vitro. However, few similar studies have been carried out in humans, and the
conclusions from these were contradictory. Using sibling human oocytes, a prospective
study was carried out to analyse the effect of 5 and 20% oxygen on prolonged development
of embryos. The outcomes measured were fertilization rate and proportion of
morphologically optimal embryos, blastocysts and optimal blastocysts developing on day 5 …