[HTML][HTML] Effects of oxygen tension on gene expression in preimplantation mouse embryos

PF Rinaudo, G Giritharan, S Talbi, AT Dobson… - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: To compare the effects of atmospheric and physiologic oxygen concentrations
on the global patterns of gene expression during mouse preimplantation development.
DESIGN: Comparative analysis of in vivo–produced and in vitro–produced embryos.
SETTING: Research laboratory. PATIENT (S): None. INTERVENTION (S): Control embryos
at the blastocyst stage that developed in vivo were collected from uteri. Experimental
embryos were obtained at the zygote stage and cultured to the blastocyst stage in Whitten's …