Basic fibroblast growth factor (BFGF) immunoreactivity as a possible link between head injury and impaired bone fracture healing
R Wildburger, N Zarkovic, G Egger, W Petek… - Bone and mineral, 1994 - Elsevier
Healing of fractures of long bones or large joints is often accelerated in patients with severe
traumatic brain injury (TBI). However, in these patients an early fracture healing is
accompanied by hypertrophic callus formation or heterotopic ossifications which might even
result in an ankylosis of the affected joints. It seems that enhanced osteogenesis in patients
suffering from TBI could be caused by some humoral factors, since the sera of these patients
strongly promote the growth of osteoblast cells in vitro. However, humoral growth promoting …
traumatic brain injury (TBI). However, in these patients an early fracture healing is
accompanied by hypertrophic callus formation or heterotopic ossifications which might even
result in an ankylosis of the affected joints. It seems that enhanced osteogenesis in patients
suffering from TBI could be caused by some humoral factors, since the sera of these patients
strongly promote the growth of osteoblast cells in vitro. However, humoral growth promoting …
